CPSA Europe 2018

Meeting Programme

Updated January 24, 2018

Tuesday February 6

1:00 PM - 4:30 pm

The King's Room


What's Your Biggest Challenge?

If it has anything to do with LC-MS, you won’t want to miss this! In its many forms, LC-MS has become a go-to technology in many industries for routine quantitative analysis. As the industry trends toward bringing this technology closer to the patient and we prepare to work together over the next two days to explore ideas for improving the ways disease is detected, we invite you to join us for an initial discussion that focuses on specific needs for quantitative LC-MS. In this unique forum, we openly encourage you to talk about your biggest challenges with one of the most popular routine analysis tools in the world. You will collaborate with your peers and discuss common challenges such as Sample Collection & Preparation, Method Development, Data Acquisition & Analysis, as well as Repair & Maintenance, but ideas around Future Business Models, Design & Form Factor, as well as Automated Workflow Integration and others are all on the table.

1:00 PM - 4:30 pm

The Queen's Room


The Future of Personalized Healthcare:
Integrated Solutions. Mapping a Path Forward.

Precision Low-Flow Pumping
Mike Lee, Milestone Development Services

Microsampling & Sample Prep
Neil Spooner, Spooner Bioanalytical Solutions

LC/MS and PicoChip: High Performance Redefined
Mike Lee, Milestone Development Services
Emily Ehrenfeld, New Objective

An Introduction to Integrative Bioinformatics and Novel Tools in Multi-Omics
Stephan Kang, Intero Life Sciences

6:00 PM - 9:00 pm

The College Suite

WELCOMe Reception

Say hello to old friends and introduce your self to new!

Wednesday February 7

7:00 AM - 8:30 AM

The Bridge Restaurant

Registration & Breakfast

8:30 AM - 8:45 AM

The Peterhouse Room

Welcome & Opening Remarks

Mike Lee

Mike Lee
Milestone Development Services

Neil Spooner

Format, Objectives, Opening Remarks
Neil Spooner
Spooner Bioanalytical Solutions

Ismael Zamora

Ismael Zamora
Molecular Discovery

8:45 am - 9:30 am

The Peterhouse Room

Plenary Lecture

Plenary Speaker

Small Molecules and Big Data: Next Generation Analytical Tools in Drug Development

Axel Pähler, Roche

9:45 am - 11:30 am

The Peterhouse Room

Session 1
Symposium Session

Is Home Sampling or even Home Measurement a Reality or a Future Dream?

Discussion Leader: Matt Barfield, GlaxoSmithKline

Remote Sampling – Impact for Innovative Clinical Trials
John Farrell, GSK

The Home Sampling/Measurement Landscape:
Location, Location, Location

Farjana Mahammed, University of Strathclyde and GSK

Strategies and Perspectives on the Impact that Microsampling Techniques have on Patient Value
John Smeraglia, UCB

Smart Trials: Bringing the Trial to the Patient
Kevin Bateman, Merck

11:45 am - 12:30 pm

The Peterhouse Room

Sponsored Lunch & Roundtable

An Integrated Workflow for Personalized Healthcare: Precision Pumping, Sample Collection and Preparation, Separations and Detection

12:45 pm - 2:15 pm

The Peterhouse Room

Session 2
Symposium Session

How can DMPK and Biotransformation Influence Future Drug Discovery and Development?

Discussion Leaders: Marie Ahlqvist, AstraZeneca and Britta Bonn, AstraZeneca

Impact of Biotransformation on “Intelligent” Design of Drugs
Emre Isin, UCB

Use of Legacy Data and How to Convert It into Knowledge
Britta Bonn, AstraZeneca

Changing the Drug Development Paradigm by Applying New Technologies Like Automated Combustion AMS
Markus Walles, Novartis

2:30 pm - 3:30 pm

The Peterhouse Room


An Integrated Workflow for Personalized Healthcare: Precision Pumping, Sample Collection and Preparation, Separations and Detection

We invite you to participate in a discussion where we will work together to identify the challenges around developing integrated solutions for personalized healthcare. In a structured workshop setting, leaders in fields of Precision Pumping, Sample Collection & Preparation, Separations, and Detection, will come together and ask strategic questions. Integral to the discussion will be the role of standardization and an assessment of whether or not it is the key to unlocking the code to integration. As we lay down the track for a journey into the future of high performance nanospray and its integral role in personalized healthcare, we will fuel this engine with inspiration, innovation, consensus and collaboration.

3:45 pm - 5:15 pm

The Peterhouse Room

Session 3
Symposium Session

Cancer and Me:
Understanding the Science to Help Find a Cure

Discussion Leader: Anthony Edge, Agilent Technologies

Understanding How Cancer Affects Me
Nikesh Patel, Agilent Technologies

Anticancer Treatments Bioanalytics - 2 Decades of New Technologies and Concepts
Jaap Wieling, Antaeus Biopharma BV

Breaking the Barrier between LC-MS and the Clinical Lab
Sarah Robinson, Thermo Fisher Scientific

5:15 pm

The Peterhouse Room


Please gather toegther to capture the 1st Annual CPSA Europe meeting with a group photo–including organizers, speakers, attendees–everyone!

6:00 pm - 8:00 pm

The College Suite

Reception & Dinner

Common Challenges, Big Ideas, and Crazy Solutions that Just Might Work

We invite you to join your colleagues for a lively evening discussion regarding important scientific problems that could potentially be solved by the application of technology. In this facilitated workshop setting, you will collaborate with your peers and discuss common challenges with Sample Collection & Preparation, Separations, Detection, as well as Data Management & Analysis. Together, we’ll prioritize the challenges and brainstorm some solutions, developing a single-voice for the needs of our industry. After the conference, a comprehensive report will be made openly available to all attendees, identified challenges will form the basis of next year’s CPSA Europe technical programme, and hopefully, some workgroups will form around high-priority challenges. Don’t miss the chance to shape the future of this meeting and tell our commercial partners exactly what challenges you face and the tools you need to address them! Hosted bar and heavy appetizers will be served.

Thursday February 8

7:00 AM - 8:30 AM

The Bridge Restaurant

Registration & Breakfast

8:30 am - 10:15 am

The Peterhouse Room

Session 4
Symposium Session

Novel Strategies for the Quantitative Analysis of Small Biological Specimens

Discussion Leader: Neil Spooner, Spooner Bioanalytical Solutions

Consider the Alternative: From Alternative Sampling Strategies Towards Alternative Detection Strategies
Christophe Stove, University of Ghent

Microsampling or Microanalysis: Considering the User in Biological Analyses
Darragh Murnane, University of Hertfordshire

Molecularly Imprinted Polymers and Sensors: Clever Technologies for Point-of-Care Diagnostics
Ute Gerhard, University of Hertfordshire

Ion Mobility: An Additional Dimension for the Analysis of Low Molecular Weight Compounds by LC-MS
Gérard Hopfgartner, University of Geneva

10:15 am - 12:00 pm

The Peterhouse Room

Session 5
Symposium Session

What is the Point of Good Science If No One Knows You’re Doing It?

Discussion Leader: Sarah Mayes, Future Science

Publishing Now and in the Future

  • How is it likely to change and what impact might this have on us?
  • How can we possibly manage this change?
Sarah Mayes, Future Science

The Messy Nightmare: Taming the Beast of Disconnected Data in the Bioanalytical Lab

  • How tech can help this
  • What else could/should be done and how this may affect the way we work together?
Shane Needham, Alturas Analytics

Sourcing and Sharing –
Challenges in Target and Disease Information

  • Ability to share this knowledge with the wider community
  • Pressure vs time to publish
Laura Rapley, GlaxoSmithKline

Journal Publication and Beyond: How Can we Make Sure the Right People See the Right Articles?

  • Open access vs subs model
  • How is social media changing the way we publish?
Laura Dormer, Future Science Group

12:00 pm - 1:00 pm

The Peterhouse Room

Sponsored Lunch & Roundtable

Generic and Pragmatic Solutions – How Good is Good Enough?

1:00 pm - 2:30 pm

The Peterhouse Room

Session 6
Symposium Session

Embracing Technological Change... When Does Disruptive Move Towards Sustaining?

Discussion Leader: Amanda Wilson, AstraZeneca

Acoustic-mist Ionisation MS: From Concept to a Game-Changer in Early Drug Discovery
Martin Bachman, AstraZeneca

Mass Cytometry (CyTOF)
Francesca Barone University of Birmingham

Fluidics and Cell Culture: Applications of Flow Open Up New Possibilities for in vitro Experimentation
David Hughes, CN Bio

2:30 pm - 3:30 pm

The Peterhouse Room


Generic and Pragmatic Solutions – How Good is Good Enough?

Join us for a frank and open discussion to work together to solve the toughest challenges in analytical chemistry. The aim is to deliver a consensus on understanding the key challenges, priorities and drivers to create and provide a solution which is fit for purpose. As a group we will discuss the specific challenges regarding affinity depletion and digestion protocols.

Following the CPSA Europe meeting we will then commit to further investigate platform agnostic solutions based on your feedback

3:30 pm - 5:00 pm

The Peterhouse Room

Session 7

Symposium Session

Lipidomics for Clinical and Pharmaceutical Applications: Challenges and Innovations

Discussion Leader: Gabriele Cruciani, Molecular Discovery

From the Screen to the Stage: Computational and Bioinformatics Challenges to bring Lipidomics into Routine Applications
Sara Tortorella, Molecular Horizon

Sebum Lipidomics Applied to the Study of Anti-Acne Properties of a Synthetic Small Molecule
Emanuela Camera, Istituti Fisioterapici Ospitalieri

Scanning Quadrupole Data Independent Analysis and Desorption Electrospray Ionization Profiling of the Lipid Content of Lysosomal Storage Disorders
Hans Vissers, Waters Corporation

5:15 pm

The Peterhouse Room

Closing Remarks

Neil Spooner, Spooner Bioanalytical Solutions
Ismael Zamora, Molecular Discovery
Mike Lee, Milestone Development Services